15A Micro-crystal X-ray diffraction
With a highly brilliance micro-focus X-ray beam, 15A aims to determine 3D crystal structures from micro-scale single crystals and non-ambient conditions.
SCIENTIFIC SCOPE
The TPS15A beamline at the Taiwan Photon Source (TPS) is a world-class facility specifically engineered for micro-crystal X-ray diffraction (μ-XRD) and advanced chemical crystallography. Exploiting a tapered cryogenic undulator source and focusing optics (such as Kirkpatrick-Baez mirrors), it delivers a high-brilliance X-ray beam with a focusing spot size as small as 10 × 10 μm² and an energy range of 9 – 35 keV. Its primary scientific scope encompasses the structural determination of challenging materials, including that only form micro-scale single crystals, complex metal-organic frameworks (MOFs), metastable states, and new functional materials.
Beyond routine structure solution, TPS15A is optimized for non-ambient crystallography, enabling researchers to probe structural transformations under extreme conditions, such as high pressure (using diamond anvil cells), ultra-low temperatures (with liquid N2 or He), and photo-excitation. Additionally, the beamline supports time-resolved pump-probe experiments with sub-nanosecond resolution and high-resolution charge density analysis, providing deep insights into chemical bonding and electronic properties.
SCIENTIFIC OPPORTUNITIES
- Challenging difficult crystal
- Metastable state structure
- Photo-induced structure
- Non-ambient conditions on crystal structure
- Pump-probe (time-resolved) structure
CORE EXPERIMENTAL TECHNIQUES
- Single crystal X-ray diffraction
- Laue diffraction
- Sub-nanosecond to sub-microsecond time-resolved structural information
- Micro-beam diffraction
- Non-ambient technique with diamond anvil cell
UNIQUE FEATURES
- Micro-size chemical crystal structural determination
- Non-ambient crystal structural characterization:
- photo-excitation
- high pressure (Up to 20 GPa or higher )
- ultra low temperature
- Pink beam Laue diffraction
- Sub-nanosecond to micro-second pump-probe single crystal X-ray diffraction
END-STATIONS
I. 15A1 Small molecule single crystal X-ray diffraction (Ready open to user)
| SPEC | 15A1 |
| Photon flux* | ~ 9.77 x 1011 photon/sec @ 18 keV with N2 gas |
| Beam size (mm) | 200 x 200; 50 x 50 by slits |
| Speed of omega/phi | 5 deg/sec |
| Speed of phi | 15 deg/sec |
| Scanning limits (W) | 0.02 sec/0.1 deg. |
| Frame rate of detector | EIGER X2 CdTe 1M 4500 Hz (8 bit); 2250 Hz (16 bit) |
| Techniques | SCXRD |
| Suitable crystal size (mm) | ~ 50 or less |
*
II. 15A2 Advanced micro-crystal X-ray diffraction (under construction)
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